工具 API

enrichr_analyzer

Perform functional enrichment analysis on a gene list. ⚠️ PREREQUISITE: Use the 'think' tool FIRST to plan your enrichment analysis strategy! Inspired by gget enrichr (Luebbert & Pachter, 2023). Uses Enrichr API: https://maayanlab.cloud/Enrichr/ Analyzes a list of genes to identify enriched: - Biological pathways (KEGG, Reactome, WikiPathways) - Gene Ontology terms (biological process, molecular function, cellular component) - Cell types and tissue expression patterns - Disease associations (GWAS Catalog) - Transcription factor targets (ChEA) Returns enrichment results with p-values, z-scores, and combined scores for each significantly enriched term. Example usage: - Analyze differentially expressed genes for pathway enrichment - Identify cell types associated with a gene signature - Find diseases associated with a gene list - Discover transcription factors regulating a set of genes Database categories: - pathway, kegg, reactome, wikipathways: Biological pathways - ontology, go_process, go_molecular, go_cellular: Gene Ontology terms - celltypes, tissues: Cell type and tissue expression - diseases, gwas: Disease associations - transcription_factors, tf: Transcription factor targets Note: This tool submits gene lists to the public Enrichr API. For single gene enrichment, consider using gene_getter with --enrich flag via CLI.